Every expansion, we count our gains and our losses. We will be missing some of our most veteran players, good and bad, and will most likely be looking to find players who can attempt to fill their voids. However, since all the raid content is at Level 85, we will casually consider all applications submitted from here on. If you are looking for a guild to level with or find some sort of "friendly" environment to immerse yourself, then feel free to throw an app for Friends & Family.
Unless you're application (or reputation) stands out from pre-Cataclysm, we won't fully consider your application until end game. You'll also have a better idea of which spots will be open in our 10/25 man raids. Cheers!